Basic Information
LncRNA/CircRNA Name | AOC4P |
Synonyms | AOC4P, AOC4, UPAT |
Region | GRCh38_17:42865922-42874369 |
Ensemble | ENSG00000260105 |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | ovarian cancer |
ICD-0-3 | C56.9 |
Methods | qPCR, Western blot etc. |
Sample | ovarian surface epithelial tissues,cell lines (HEY-A8 and HEY, HO8910-PM and HO8910, and SKOV3-IP and SKOV3) |
Expression Pattern | down-regulated |
Function Description | The results showed that AOC4P expression levels were decreased in EOC tissues and cell lines, and that the under-expression of AOC4P was positively correlated with FIGO stage and lymph node metastasis. |
Pubmed ID | 32334623 |
Year | 2020 |
Title | Long non-coding RNA AOC4P suppresses epithelial ovarian cancer metastasis by regulating epithelial-mesenchymal transition. |
External Links
Links for AOC4P | GenBank HGNC NONCODE |
Links for ovarian cancer | OMIM COSMIC |