Basic Information
| LncRNA/CircRNA Name | LINC01554 |
| Synonyms | NA |
| Region | GRCh38_5:95852232-95860133 |
| Ensemble | ENSG00000236882 |
| Refseq | NR_026936 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | HCC tissues, cell lines (PLC, Hep3B, Huh7, SMMC-7721, QSG-7701 ) |
| Expression Pattern | down-regulated |
| Function Description | Compared to correspongding adjacent liver tissues, the LINC01554 expression in HCC was significantly down-regulated (P=0.001). And its expression levels in HCC cell lines were also remarkably lower than that in normal human hepatocyte cell line (P<0.001). Besides, the expression level of LINC01554 was significantly related to tumor size, multiple lesions, TNM stages, tumor recurrence rate as well as long-term survival in HCC patients (P<0.05). |
| Pubmed ID | 32231743 |
| Year | 2020 |
| Title | Down-regulation of Long Non-coding RNA LINC01554 in Hepatocellular Cancer and Its Clinical Significance |
External Links
| Links for LINC01554 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |