Basic Information
| LncRNA/CircRNA Name | LINC01420 |
| Synonyms | NBDY, LINC01420, NoBody |
| Region | GRCh38_X:56729241-56818380 |
| Ensemble | ENSG00000204272 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR, RNAi, Cell migration and invasion assay, ISH etc. |
| Sample | NPC tissues, cell lines (HNE1, HK-1, HNE2 and 5-8F) |
| Expression Pattern | up-regulated |
| Function Description | The expression level of LINC01420 in NPC tissues were higher than nasopharyngeal epithelial (NPE) tissues. Moreover, NPC patients with high LINC01420 expression level showed poor overall survival. Knockdown LINC01420 inhibited NPC cell migration and invasion in vitro. |
| Pubmed ID | 28123602 |
| Year | 2017 |
| Title | High Expression of LINC01420 indicates an unfavorable prognosis and modulates cell migration and invasion in nasopharyngeal carcinoma. |
External Links
| Links for LINC01420 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |