Basic Information
| LncRNA/CircRNA Name | LINC01420 |
| Synonyms | NBDY, LINC01420, NoBody |
| Region | GRCh38_X:56729241-56818380 |
| Ensemble | ENSG00000204272 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Luciferase reporter assay, Western blot, RIP |
| Sample | PC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | The bioinformatics analyses revealed LINC01420 was highly expressed in PC tissues. Besides, LINC01420 was pronouncedly upregulated in PC cell lines and its depletion controlled PC cell proliferation and EMT in vitro and hindered tumor growth in vivo. |
| Pubmed ID | 31562613 |
| Year | 2019 |
| Title | Long Non-coding RNA LINC01420 Contributes to Pancreatic Cancer Progression Through Targeting KRAS Proto-oncogene. |
External Links
| Links for LINC01420 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |