Basic Information
| LncRNA/CircRNA Name | LINC01410 |
| Synonyms | NA |
| Region | GRCh38_9:62801461-62813486 |
| Ensemble | ENSG00000238113 |
| Refseq | NR_121647 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | 2 | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, Western blot, Luciferase reporter assay, RIP |
| Sample | CCA tissues,CCA cells (CCLP1, HuCCT1, HuH-28, RBE, QBC939) and human intrahepatic bile duct epithelium cell (HIBEC) |
| Expression Pattern | up-regulated |
| Function Description | The high expression of LINC01410 was proved in CCA tissues and CCA cell lines. Also, CCA patients with high LINC01410 level presented poor prognosis. LINC01410 deficiency impeded cell proliferation, migration and invasion in HuCCT1 and RBE cell lines. What's more, LINC01410 interacted with miR-124-3p. |
| Pubmed ID | 31951299 |
| Year | 2020 |
| Title | LINC01410 Promotes Cell Proliferation and Migration of Cholangiocarcinoma Through Modulating miR-124-3p/SMAD5 Axis |
External Links
| Links for LINC01410 | GenBank HGNC NONCODE |
| Links for cholangiocarcinoma | OMIM COSMIC |