Basic Information
| LncRNA/CircRNA Name | LINC01352 |
| Synonyms | NA |
| Region | GRCh38_1:220829255-220832429 |
| Ensemble | ENSG00000238078 |
| Refseq | NR_110797 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot |
| Sample | HCC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | downregulation of LINC01352, which acts as an endogenous sponge, increases the expression of miR-135b, leading to the reduced production of adenomatous polyposis coli (APC), consequently activating Wnt/?-catenin signalling to facilitate tumour progression. |
| Pubmed ID | 32157216 |
| Year | 2020 |
| Title | HBx/ER? complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis |
External Links
| Links for LINC01352 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |