Basic Information
| LncRNA/CircRNA Name | LINC01305 |
| Synonyms | NA |
| Region | GRCh38_2:174326027-174330643 |
| Ensemble | ENSG00000231453 |
| Refseq | NR_038897 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP, etc. |
| Sample | Cervical cancer cell lines SiHa, Hela, C-33A, Ca ski, ME-180, MS751 |
| Expression Pattern | up-regulated |
| Function Description | lncRNA LINC01305 silencing suppresses EMT, invasion and migration via repressing the PI3K/Akt signalling pathway by means of targeting TNXB in CC cells, which ultimately provides novel insight and identification of potential therapeutic targets for CC. |
| Pubmed ID | 30697971 |
| Year | 2019 |
| Title | LncRNA LINC01305 silencing inhibits cell epithelial-mesenchymal transition in cervical cancer by inhibiting TNXB-mediated PI3K/Akt signalling pathway. |
External Links
| Links for LINC01305 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |