Basic Information
| LncRNA/CircRNA Name | LINC01194 |
| Synonyms | NA |
| Region | GRCh38_5:12574857-12804363 |
| Ensemble | ENSG00000248131 |
| Refseq | NR_033383 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | NSCLC and adjacent non-lesional tissue,cell lines (A549, H1299, H460, H1975,BES-2B) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA LINC01194 was highly expressed in NSCLC tissues and NSCLC lines.LncRNA LINC01194 was able to inhibit miR-486-5p expression and upregulate the expression level of CDK4. |
| Pubmed ID | 32346298 |
| Year | 2020 |
| Title | The lncRNA LINC01194/miR-486-5p Axis Facilitates Malignancy in Non-Small Cell Lung Cancer via Regulating CDK4. |
External Links
| Links for LINC01194 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |