Basic Information
| LncRNA/CircRNA Name | LINC01048 |
| Synonyms | NA |
| Region | GRCh38_13:37481467-37484769 |
| Ensemble | ENSG00000230390 |
| Refseq | NR_125762 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cutaneous squamous cell carcinoma |
| ICD-0-3 | C49 |
| Methods | qPCR, Luciferase reporter assay, Western blot, Microarray, RIP |
| Sample | CSCC tissues,cell lines (SCC13,SCL-1) |
| Expression Pattern | up-regulated |
| Function Description | USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1. |
| Pubmed ID | 30931936 |
| Year | 2019 |
| Title | USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1. |
External Links
| Links for LINC01048 | GenBank HGNC NONCODE |
| Links for cutaneous squamous cell carcinoma | OMIM COSMIC |