Basic Information
| LncRNA/CircRNA Name | LINC00994 |
| Synonyms | NA |
| Region | GRCh38_3:64078361-64087363 |
| Ensemble | ENSG00000189196 |
| Refseq | NR_033978 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Microarray, Luciferase reporter assay, western blot |
| Sample | pancreatic tissue,cell lines(Panc-1,AsPC-1 ) |
| Expression Pattern | up-regulated |
| Function Description | Our microarray results first indicated long intergenic non-protein coding RNA 994 (LINC00994) as an upregulated long non-coding RNA (lncRNA) and miR-765-3p as a downregulated microRNA (miRNA) in pancreatic cancer tissues |
| Pubmed ID | 30739523 |
| Year | 2019 |
| Title | Inhibition of LINC00994 represses malignant behaviors of pancreatic cancer cells: interacting with miR-765-3p/RUNX2 axis. |
External Links
| Links for LINC00994 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |