Basic Information
LncRNA/CircRNA Name | LINC00982 |
Synonyms | NA |
Region | GRCh38_1:3059615-3068437 |
Ensemble | ENSG00000177133 |
Refseq | NR_015440 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | lung adenocarcinoma |
ICD-0-3 | C34 |
Methods | qPCR |
Sample | cell lines (A549, H1299, H1975, BEAS-2B) |
Expression Pattern | down-regulated |
Function Description | We found that LUAD patients demonstrated lower expression and copy number variation but higher methylation of long intergenic non-protein coding RNA 982 (LINC00982) and PR domain containing 16 (PRDM16) compared with controls. patients with low expression of LINC00982, PRDM16 or both, showed poorer survival than the groups with high expression of LINC00982, PRDM16. |
Pubmed ID | 30132554 |
Year | 2018 |
Title | Low expression of LINC00982 and PRDM16 is associated with altered gene expression, damaged pathways and poor survival in lung adenocarcinoma. |
External Links
Links for LINC00982 | GenBank HGNC NONCODE |
Links for lung adenocarcinoma | OMIM COSMIC |