Basic Information
| LncRNA/CircRNA Name | LINC00978 |
| Synonyms | MIR4435-2HG, AGD2, AK001796, LINC00978, MIR4435-1HG, MIR4435-2HG |
| Region | GRCh38_2:111036776-111523376 |
| Ensemble | ENSG00000172965 |
| Refseq | NR_015395 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | breast cancer tissues, cell lines (MCF10A, MDA-MB-231, ZR751, ZR7530, MCF-7, SKBR3, BCAP37 etc.) |
| Expression Pattern | up-regulated |
| Function Description | Here, we identify a lncRNA, LINC00978, which is upregulated in breast cancer cell lines and tissues compared with corresponding controls. Furthermore, LINC00978 expression is negatively associated with hormone receptor (HR) status in 195 breast cancer patients studied. |
| Pubmed ID | 27897214 |
| Year | 2016 |
| Title | LINC00978 predicts poor prognosis in breast cancer patients. |
External Links
| Links for LINC00978 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |