Basic Information
| LncRNA/CircRNA Name | LINC00978 |
| Synonyms | NA |
| Region | GRCh38_2:111036776-111523376 |
| Ensemble | ENSG00000172965 |
| Refseq | NR_015395 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | RNAi, RT-qPCR, Western blot |
| Sample | HCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00978 is highly expressed in human HCC tissue and correlates with poor HCC prognosis. LINC00978 promotes HCC cell proliferation, cell cycle progression, and survival, partially by activating the MAPK/ERK pathway. |
| Pubmed ID | 32077915 |
| Year | 2020 |
| Title | LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway |
External Links
| Links for LINC00978 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |