Basic Information
| LncRNA/CircRNA Name | LINC00973 |
| Synonyms | NA |
| Region | GRCh38_3:98981058-98983096 |
| Ensemble | ENSG00000240476 |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | CRC tissues ,cell line(H508/CR ) |
| Expression Pattern | up-regulated |
| Function Description | In addition, lncRNA LINC00973 was upregulated in the H508/CR cell line and cells transfected with a LINC00973 short interfering RNA exhibited reduced cell viability, increased apoptosis, and decreased glucose consumption and lactate secretion. |
| Pubmed ID | 30848094 |
| Year | 2019 |
| Title | Long noncoding RNA and mRNA profiling in cetuximab-resistant colorectal cancer cells by RNA sequencing analysis. |
External Links
| Links for LINC00973 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |