Basic Information
| LncRNA/CircRNA Name | LINC00963 |
| Synonyms | NA |
| Region | GRCh38_9:129483451-129513686 |
| Ensemble | ENSG00000204054 |
| Refseq | NR_038955 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | Microarray, qPCR, RNAi, Western blot etc. |
| Sample | cell lines (LNCaP, C4-3) |
| Expression Pattern | up-regulated |
| Function Description | Linc00963 was upregulated most obviously evaluated by qPCR. Knockdown of linc00963 attenuated C4-2 cell proliferation, motility, invasion ability, the expression of EGFR and phosphorylation levels of AKT, and promoted cell apoptosis. |
| Pubmed ID | 24691949 |
| Year | 2014 |
| Title | Linc00963: a novel, long non-coding RNA involved in the transition of prostate cancer from androgen-dependence to androgen-independence. |
External Links
| Links for LINC00963 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |