Basic Information
| LncRNA/CircRNA Name | LINC00958 |
| Synonyms | NA |
| Region | GRCh38_11:12961842-12989548 |
| Ensemble | ENSG00000251381 |
| Refseq | NR_038904 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | LUSC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | we explored a newly-discovered intergenic lncRNA LINC00958 in NSCLC.LINC00958 facilitates tumorigenesis in NSCLC by activating JNK/c-JUN signaling pathway, indicating a new road for diagnosis and treatment of both LUAD and LUSC. |
| Pubmed ID | 31752512 |
| Year | 2019 |
| Title | LINC00958 accelerates cell proliferation and migration in non-small cell lung cancer through JNK/c-JUN signaling |
External Links
| Links for LINC00958 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |