Basic Information
| LncRNA/CircRNA Name | LINC00942 |
| Synonyms | LINC00942 |
| Region | GRCh38_12:1500525-1507318 |
| Ensemble | ENSG00000249628 |
| Refseq | NR_028415 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | cell line (A549, H838) |
| Expression Pattern | differential expression |
| Function Description | Three repressed lncRNAs were further evaluated with RT-qPCR: LINC00942, RP11-284F21.7 and RP11-345L23.1. In all cases, this confirmed responsiveness to NFE2L2 siRNA silencing in A549, as well as one additional lung cancer cell line, H838, which similarly harbours a loss-of-function mutation in KEAP1 |
| Pubmed ID | 28959951 |
| Year | 2016 |
| Title | Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events |
External Links
| Links for LINC00942 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |