Basic Information
| LncRNA/CircRNA Name | LINC00899 |
| Synonyms | NA |
| Region | GRCh38_22:46039907-46044853 |
| Ensemble | ENSG00000231711 |
| Refseq | NR_027036 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, other |
| Sample | Serum samples, GC cell lines AGS,SGC-7901, MGC-803, and MKN-45 |
| Expression Pattern | up-regulated |
| Function Description | Higher expression of serum LINC00899 was positively associated with FAB classification and cytogenetics. Moreover, ROC curve analyses showed that serum LINC00899 could discriminate AML patients from healthy controls with the area under the curve (AUC) of 0.807. In addition, the serum LINC00899 expression level was significantly reduced when the patients achieved complete remission. Kaplan-Meier analysis showed that patients with high serum LINC00899 expression had a shorter overall survival compared with the low serum LINC00899 expression group).? |
| Pubmed ID | 30468482 |
| Year | 2018 |
| Title | Long Non-Coding RNA LINC00899 as a Novel Serum Biomarker for Diagnosis and Prognosis Prediction of Acute Myeloid Leukemia |
External Links
| Links for LINC00899 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |