Basic Information
| LncRNA/CircRNA Name | LINC00707 |
| Synonyms | NA |
| Region | GRCh38_10:6779598-6842906 |
| Ensemble | ENSG00000238266 |
| Refseq | NR_038291 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western blot, RIP |
| Sample | CRC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | The upregulation of LINC00707 expression was significantly associated with tumor size, stage and poor survival in patients with CRC. Knockdown of LINC00707 may inhibit the proliferation of CRC cells by binding with miR-485-5p. |
| Pubmed ID | 32010320 |
| Year | 2020 |
| Title | Long non-coding RNA LINC00707 acts as a competing endogenous RNA to enhance cell proliferation in colorectal cancer |
External Links
| Links for LINC00707 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |