Basic Information
| LncRNA/CircRNA Name | LINC00682 |
| Synonyms | long intergenic non-protein coding RNA 682 |
| Region | GRCh38_4:41872747-41882955 |
| Ensemble | ENSG00000245870 |
| Refseq | NR_104143 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, luciferase reporter assay, Western blotting |
| Sample | AGS cells,Human tissues |
| Expression Pattern | down-regulated |
| Function Description | We show that ectopic overexpression of LINC00682 induced miR-9 downregulation but LMX1A upregulation, inhibiting AGS cell survival, proliferation, migration and invasion. Significant apoptosis activation was detected in LINC00682-overexpressed AGS cells.LINC00682 expression levels are significantly downregulated in human GC tissues. |
| Pubmed ID | 31822638 |
| Year | 2019 |
| Title | LINC00682 Inhibits Gastric Cancer Cell Progression via Targeting microRNA-9-LMX1A Signaling Axis |
External Links
| Links for LINC00682 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |