Basic Information
| LncRNA/CircRNA Name | LINC00680 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000215190 |
| Refseq | NR_125727 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | PCR, Western blot |
| Sample | glioblastoma tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | we detected that LINC00680 and TTN-AS1 were upregulated in glioblastoma cells.LINC00680 and TTN-AS1 promoted glioblastoma cell malignant biological behaviors via the miR-320b/EGR3/PKP2 axis by being stabilized by EIF4A3, which may provide a novel strategy for glioblastoma therapy. |
| Pubmed ID | 32000032 |
| Year | 2019 |
| Title | LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells |
External Links
| Links for LINC00680 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |