Basic Information
LncRNA/CircRNA Name | LINC00673 |
Synonyms | NA |
Region | GRCh38_1:29554-31109 |
Ensemble | |
Refseq | NR_036488 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | PCR |
Sample | lung adenocarcinoma tissues |
Expression Pattern | down-regulated |
Function Description | For example, SNPs can affect the expression of their relevant lncRNAs.Different SNP genotype in LINC00673 may affect its binding to miR-1231, which alters the miRNA's activity and influences PTPN11 (protein tyrosine phosphatase, non-receptor type 11) degradation in an allele-specific manner |
Pubmed ID | 30980423 |
Year | 2019 |
Title | SNPs in LncRNA genes are associated with non-small cell lung cancer in a Chinese population. |
External Links
Links for LINC00673 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |