Basic Information
| LncRNA/CircRNA Name | ANRIL |
| Synonyms | CDKN2B-AS1, ANRIL, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, p15AS |
| Region | GRCh38_9:21994778-22121097 |
| Ensemble | ENSG00000240498 |
| Refseq | NR_003529 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | cell line U2OS |
| Expression Pattern | up-regulated |
| Function Description | The expression of lncRNA ANRIL is increased in hepatocellular carcinoma, and demonstrated that it serves a role in tumor proliferation and metastasis. The results of these studies therefore suggest that dysregulation of ANRIL may be a contributing factor in human cancer progression. |
| Pubmed ID | 29201225 |
| Year | 2017 |
| Title | Long non-coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells |
External Links
| Links for ANRIL | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |