Basic Information
LncRNA/CircRNA Name | LINC00668 |
Synonyms | NA |
Region | GRCh38_18:6919496-6929966 |
Ensemble | ENSG00000265933 |
Refseq | NR_034100 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qRT-PCR, Western blot |
Sample | breast cancer tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | Linc00668 associated with staphylococcal nuclease domain-containing 1 (SND1) and regulated the expression of downstream genes.Our observations suggest that Linc00668 promotes metastasis, and chemotherapeutic resistance in breast cancer by interacting with SND1. |
Pubmed ID | 32117742 |
Year | 2020 |
Title | Linc00668 Promotes Invasion and Stem Cell-Like Properties of Breast Cancer Cells by Interaction With SND1 |
External Links
Links for LINC00668 | GenBank HGNC NONCODE |
Links for breast cancer | OMIM COSMIC |