Basic Information
| LncRNA/CircRNA Name | LINC00665 |
| Synonyms | NA |
| Region | GRCh38_19:36313067-36331718 |
| Ensemble | ENSG00000232677 |
| Refseq | NR_038278 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | lung cancer tissues,cell line (PC9) |
| Expression Pattern | up-regulated |
| Function Description | We showed that long intergenic non-coding RNA 00665 expression was significantly upregulated in lung cancer tissues and cells with acquired gefitinib resistance. |
| Pubmed ID | 30889481 |
| Year | 2019 |
| Title | LINC00665 Induces Acquired Resistance to Gefitinib through Recruiting EZH2 and Activating PI3K/AKT Pathway in NSCLC. |
External Links
| Links for LINC00665 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |