Basic Information
| LncRNA/CircRNA Name | LINC00657 |
| Synonyms | NORAD, LINC00657, ASHGA5P032173 |
| Region | GRCh38_20:36045618-36050960 |
| Ensemble | ENSG00000260032 |
| Refseq | NR_027451 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | Microarray, qPCR |
| Sample | laryngeal squamous cell carcinoma tissues |
| Expression Pattern | down-regulated |
| Function Description | the downregulation of miR-486-5p, LINC00657, CTC-297N7.9, we then established the LINC00657 subnetwork to predict its function. KEGG pathway analysis showed that the relevant mRNAs were primarily enriched in colorectal cancer (hsa05210), endocytosis (hsa04144), and microRNAs in cancer pathway (hsa05206). |
| Pubmed ID | 30128795 |
| Year | 2018 |
| Title | Comprehensive analysis of the whole coding and non-coding RNA transcriptome expression profiles and construction of the circRNA-lncRNA co-regulated ceRNA network in laryngeal squamous cell carcinoma. |
External Links
| Links for LINC00657 | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell cancer | OMIM COSMIC |