Basic Information
| LncRNA/CircRNA Name | LINC00599 |
| Synonyms | NA |
| Region | GRCh38_8:9900064-9905366 |
| Ensemble | ENSG00000253230 |
| Refseq | NR_024281 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | glioma tissues,cell lines (SHG-44, SW1783, U251, and LN229) |
| Expression Pattern | up-regulated |
| Function Description | In vitro study suggested up-regulation of LINC00599 depressed glioma cell migration and invasion through regulating epithelial-mesenchymal transition (EMT) process. In conclusion, LINC00599 acts as a tumor-suppressing long non-coding RNA (lncRNA) in glioma. |
| Pubmed ID | 30867254 |
| Year | 2019 |
| Title | Low LINC00599 expression is a poor prognostic factor in glioma. |
External Links
| Links for LINC00599 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |