Basic Information
| LncRNA/CircRNA Name | LINC00520 |
| Synonyms | NA |
| Region | GRCh38_14:55781135-55796688 |
| Ensemble | ENSG00000258791 |
| Refseq | NR_026796 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western blot |
| Sample | CRC tissues,cell lines (HCT116, SW480, HT29, and Lovo) |
| Expression Pattern | up-regulated |
| Function Description | interference of LINC00520 resulted in a significant decrease of CRC cell proliferation, migration, colony forming ability, and invasion. |
| Pubmed ID | 32146708 |
| Year | 2020 |
| Title | Long noncoding RNA LINC00520 accelerates the?progression of colorectal cancer by?serving as?a?competing endogenous RNA of microRNA-577 to?increase HSP27 expression |
External Links
| Links for LINC00520 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |