Basic Information
| LncRNA/CircRNA Name | LINC00518 |
| Synonyms | NA |
| Region | GRCh38_6:10429255-10434874 |
| Ensemble | ENSG00000183674 |
| Refseq | NR_027793 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Cervical Cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot |
| Sample | CC tissues, cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that LINC00518 was upregulated in CC tissues and associated with International Federation of Gynaecology and Obstetrics (FIGO) stage, lymph node metastasis, depth of cervical invasion and poor survival of CC patients. |
| Pubmed ID | 30720156 |
| Year | 2019 |
| Title | Knockdown of long non-coding RNA LINC00518 inhibits cervical cancer proliferation and metastasis by modulating JAK/STAT3 signaling. |
External Links
| Links for LINC00518 | GenBank HGNC NONCODE |
| Links for Cervical Cancer | OMIM COSMIC |