Basic Information
| LncRNA/CircRNA Name | LINC00511 |
| Synonyms | NA |
| Region | GRCh38_17:72323123-72640472 |
| Ensemble | ENSG00000227036 |
| Refseq | NR_033876 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qRT-PCR, Western blot analysis, RIP |
| Sample | ESR1-expressing OV cell lines, including CAOV3, OVCAR3 and SKOV3, as well as ESR1-losing OV cell line (UWB1.289) |
| Expression Pattern | up-regulated |
| Function Description | ESR1 transcriptionally regulated LINC00511 expression. Up-regulated LINC00511 promoted the viability, migration and invasion of CAOV3 cells with the inhibition of the apoptosis. |
| Pubmed ID | 31920390 |
| Year | 2019 |
| Title | Long Non-Coding RNA LINC00511 Mediates the Effects of ESR1 on Proliferation and Invasion of Ovarian Cancer Through miR-424-5p and miR-370-5p |
External Links
| Links for LINC00511 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |