Basic Information
LncRNA/CircRNA Name | LINC00472 |
Synonyms | LINC00472, C6orf155 |
Region | GRCh38_6:71344344-71420769 |
Ensemble | ENSG00000233237 |
Refseq | NR_121612 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | lung adenocarcinoma |
ICD-0-3 | C34 |
Methods | qPCR |
Sample | lung adenocarcinoma tissues |
Expression Pattern | down-regulated |
Function Description | Our study sheds novel light on the roles of lncRNA-related ceRNA network in LAD and facilitates the detection of potential lncRNA biomarkers for LAD diagnosis and treatment. Remarkably, in our study, LINC00472, HCP5, and SNHG12 might be potential biomarkers for LAD management.As we all know, histones constantly undergo post-translational modifications, for instance, methylation, acetylation.Typically, lncRNA functions are characterized using a ??uilt by association??trategy. It has been reported that lncRNAs harboring miRNA response elements (MREs) serve as competing endogenous RNAs (ceRNAs) to exchange with mRNAs via competing for common miRNAs. |
Pubmed ID | 28793054 |
Year | 2017 |
Title | Revealing potential long non-coding RNA biomarkers in lung adenocarcinoma using long non-coding RNA-mediated competitive endogenous RNA network. |
External Links
Links for LINC00472 | GenBank HGNC NONCODE |
Links for lung adenocarcinoma | OMIM COSMIC |