Basic Information
| LncRNA/CircRNA Name | LINC00467 |
| Synonyms | NA |
| Region | GRCh38_1:211382803-211435333 |
| Ensemble | ENSG00000153363 |
| Refseq | NR_026761 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | RT-qPCR, Western blot analysis, RIP, Luciferase reporter assay |
| Sample | LAD tissues,LAD cell lines (SPC-A1, A549, Calu3, and H1299) and human bronchial epithelial cells (BEAS-2B) |
| Expression Pattern | up-regulated |
| Function Description | LINC00467 expressed higher in LAD tissues and cell lines, and increased LINC00467 indicated a poor prognosis. Knockdown of LINC00467 inhibited cell proliferation, the expressions of tumor stem cell-related genes, and cell spheroid formation ability, while it promoted cell apoptosis. |
| Pubmed ID | 31680321 |
| Year | 2019 |
| Title | LINC00467 Promotes Cell Proliferation and Stemness in Lung Adenocarcinoma by Sponging miR-4779 and miR-7978 |
External Links
| Links for LINC00467 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |