Basic Information
| LncRNA/CircRNA Name | LINC00467 |
| Synonyms | NA |
| Region | GRCh38_1:211382803-211435333 |
| Ensemble | ENSG00000153363 |
| Refseq | NR_026761 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | RT-PCR, Western blot analysis, Luciferase assay |
| Sample | LUAD tissues,LUAD cell lines H1299, H23, A549, and HCC827 and normal lung fibroblast cell line IMR90 |
| Expression Pattern | up-regulated |
| Function Description | linc00467 expression was elevated in LUAD tissues and correlated with overall survival of LUAD patients. Linc00467 knockdown resulted in reduced proliferation rate in lung cancer cells. Furthermore, we elucidated that linc00467 promoted CCND1 expression in lung cancer cells via functioning as a molecular sponge for miR-20b-5p. |
| Pubmed ID | 31686834 |
| Year | 2019 |
| Title | Linc00467 Promotes Lung Adenocarcinoma Proliferation via Sponging miR-20b-5p to Activate CCND1 Expression |
External Links
| Links for LINC00467 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |