Basic Information
| LncRNA/CircRNA Name | LINC00467 |
| Synonyms | NA |
| Region | GRCh38_1:211382803-211435333 |
| Ensemble | ENSG00000153363 |
| Refseq | NR_026761 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, RIP etc |
| Sample | glioma tissues, cell lines (LN229, LN308, U87, LN229,HEB ) |
| Expression Pattern | up-regulated |
| Function Description | The expression of LINC00467 was significantly up-regulated in tumor samples than that in normal samples, which was not correlated with patient survival time. Besides, expression of LINC00467 was higher in glioma cells than that of negative control cells. Upregulation of LINC00467 promoted proliferative and invasive abilities, and accelerated cell cycle in G0/G1 phase of U87 and LN229 cells. |
| Pubmed ID | 32226508 |
| Year | 2020 |
| Title | Long Noncoding RNA LINC00467 Promotes Glioma Progression Through Inhibiting P53 Expression via Binding to DNMT1 |
External Links
| Links for LINC00467 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |