Basic Information
| LncRNA/CircRNA Name | LINC00467 |
| Synonyms | NA |
| Region | GRCh38_1:211382803-211435333 |
| Ensemble | ENSG00000153363 |
| Refseq | NR_026761 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck squamous cell carcinoma |
| ICD-0-3 | C76.0 |
| Methods | RT-qPCR, Western blot |
| Sample | HNSCC cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00467 was considerably upregulated in HNSCC cells, and absence of LINC00467 suppressed cell growth, cell migration and EMT process in HNSCC.LINC00467 enhances HNSCC progression by serving as a sponge of miR-299-5p to increase USP48 expression. |
| Pubmed ID | 32159247 |
| Year | 2020 |
| Title | LINC00467 enhances head and neck squamous cell carcinoma progression and epithelial-mesenchymal transition process via miR-299-5p/ubiquitin specific protease-48 axis |
External Links
| Links for LINC00467 | GenBank HGNC NONCODE |
| Links for head and neck squamous cell carcinoma | OMIM COSMIC |