Basic Information
| LncRNA/CircRNA Name | LINC00460 |
| Synonyms | NA |
| Region | GRCh38_13:106374477-106384315 |
| Ensemble | ENSG00000233532 |
| Refseq | NR_034119 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | CRC tissue, cell lines (HT29 and LOVO) |
| Expression Pattern | up-regulated |
| Function Description | We found that LINC00460 was upregulated and closely correlated to clinicopathological features and poor prognosis of patients with CRC. Functionally, we elucidated that LINC00460 promoted metastasis in CRC cell lines HT29 and LOVO. |
| Pubmed ID | 30863183 |
| Year | 2019 |
| Title | lncRNA LINC00460 promoted colorectal cancer cells metastasis via miR-939-5p sponging. |
External Links
| Links for LINC00460 | GenBank HGNC NONCODE |
| Links for Colorectal cancer | OMIM COSMIC |