Basic Information
| LncRNA/CircRNA Name | LINC00460 |
| Synonyms | NA |
| Region | GRCh38_13:106374477-106384315 |
| Ensemble | ENSG00000233532 |
| Refseq | NR_034119 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | Gefitinib | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc |
| Sample | cell lines(A549 (CCL-185), H1299 (CRL-5803) and H1975 (CRL-5908)) |
| Expression Pattern | up-regulated |
| Function Description | LINC00460 expression was found to be significantly higher in lung cancer cell lines with EGFR-activating mutations than in wild-type cell lines . |
| Pubmed ID | 31789388 |
| Year | 2019 |
| Title | Clinical importance of long non-coding RNA LINC00460 expression in EGFR-mutant lung adenocarcinoma |
External Links
| Links for LINC00460 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |