Basic Information
| LncRNA/CircRNA Name | LINC00365 |
| Synonyms | NA |
| Region | GRCh38_13:30103178-30108875 |
| Ensemble | ENSG00000224511 |
| Refseq | NR_046998 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RT-qPCR, Western blot assay, Luciferase reporter assay |
| Sample | breast cancer and paracancerous tissues, invasive ductal carcinoma cell lines MCF-7 and T47D,breast epithelial MCF-10A cells |
| Expression Pattern | down-regulated |
| Function Description | the overexpression of LINC00365 and SCGB2A1 inhibited cell viability and induced cell apoptosis through the inhibition of the NF-?B signaling pathway in breast cancer cells. |
| Pubmed ID | 31897191 |
| Year | 2020 |
| Title | LINC00365-SCGB2A1 Axis Inhibits the Viability of Breast Cancer Through Targeting NF-?B Signaling |
External Links
| Links for LINC00365 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |