Basic Information
| LncRNA/CircRNA Name | LINC00346 |
| Synonyms | NA |
| Region | GRCh38_13:110863987-110870251 |
| Ensemble | ENSG00000255874 |
| Refseq | NR_027701 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot |
| Sample | HCC cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00346 could regulate the expression of CDK1/CCNB1 through the competitive adsorption of miR-199a-3p, thereby affecting the p53 signaling pathway and finally regulating the apoptosis, invasion and cell cycle of HCC cells. |
| Pubmed ID | 32133348 |
| Year | 2020 |
| Title | LINC00346 Acts as a Competing Endogenous RNA Regulating Development of Hepatocellular Carcinoma via Modulating CDK1/CCNB1 Axis |
External Links
| Links for LINC00346 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |