Basic Information
LncRNA/CircRNA Name | LINC00324 |
Synonyms | C17orf44,NCRNA00324 |
Region | GRCh38_7:8220642-8224043 |
Ensemble | ENSG00000178977 |
Refseq | NR_026951 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot, RIP, etc. |
Sample | gastric cancer tissues, cell lines (SGC7901, BGC823, MGC803, AGS, GES-1) |
Expression Pattern | up-regulated |
Function Description | The overexpression of LINC00324 was correlated with advanced TNM stage, larger tumor size, and lymph node metastasis as well as poor prognosis. LINC00324 could combine with the RNA-binding protein (RBP) human antigen R (HuR) and thus stabilize the expression of FAM83B. |
Pubmed ID | 29915327 |
Year | 2018 |
Title | Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression. |
External Links
Links for LINC00324 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |