Basic Information
| LncRNA/CircRNA Name | LINC00319 |
| Synonyms | NA |
| Region | GRCh38_21:43446601-43453893 |
| Ensemble | ENSG00000188660 |
| Refseq | NR_026960 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qRT-PCR, Western blot, Luciferase reporter assays, RIP |
| Sample | cancer tissues,cell (H8) and cervical cancer cells (SiHa, HeLa, CaSki, and C-33A) |
| Expression Pattern | up-regulated |
| Function Description | LINC00319 was highly expressed in tissues and cell lines in cervical cancer. Further, overexpression of LINC00319 accelerates cell migration, invasion and EMT in cervical cancer. Moreover, LINC00319 could bind with miR-3127-5p and negatively regulated its expression. |
| Pubmed ID | 31942724 |
| Year | 2020 |
| Title | LINC00319 Promotes Migration, Invasion and Epithelial-Mesenchymal Transition Process in Cervical Cancer by Regulating miR-3127-5p/RPP25 Axis |
External Links
| Links for LINC00319 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |