Basic Information
| LncRNA/CircRNA Name | LINC00313 |
| Synonyms | C21orf84, NCRNA00313, CH507-42P11.5 |
| Region | GRCh38_21:43462094-43479534 |
| Ensemble | ENSG00000185186 |
| Refseq | NR_026863 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, etc. |
| Sample | PTC tissues, cell lines (K1, IHH4, MDA-T32, NPA87, TPC-1, Nthy-ori3-1) |
| Expression Pattern | up-regulated |
| Function Description | HOTAIR overexpression is sufficient to induce, whereas knockdown of HOTAIR suppressed NED of PCa cells. HOTAIR may participate in PCa progression. |
| Pubmed ID | 29940766 |
| Year | 2018 |
| Title | Long noncoding RNA LINC00313 modulates papillary thyroid cancer tumorigenesis via sponging miR-4429. |
External Links
| Links for LINC00313 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |