Basic Information
| LncRNA/CircRNA Name | LINC00312 |
| Synonyms | LINC00312, ERR-10, ERR10, LMCD1DN, LOH3CR2A, NAG-7, NAG7, NCRNA00312 |
| Region | NA |
| Ensemble | NA |
| Refseq | NR_024065 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Western blot etc. |
| Sample | bladder cancer tissues, cell lines (T24, BIU87, and 5637) |
| Expression Pattern | down-regulated |
| Function Description | qRT-PCR indicated that LINC00312 expression was lower but miR-197-3p expression was higher in BC tissues compared with adjacent tissues; LINC00312 was negatively correlated with miR-197-3p. The migration test revealed that the downregulation of miR-197-3p and overexpression of LINC00312 inhibited cell migration and invasion abilities, while the overexpression of miR-197-3p and the upregulation of LINC00312 promoted cell migration and invasion. |
| Pubmed ID | 27631965 |
| Year | 2016 |
| Title | LINC00312 inhibits the migration and invasion of bladder cancer cells by targeting miR-197-3p. |
External Links
| Links for LINC00312 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |