Basic Information
LncRNA/CircRNA Name | LINC00261 |
Synonyms | LINC00261, ALIEN, C20orf56, DEANR1, HCCDR1, NCRNA00261, onco-lncRNA-17 |
Region | GRCh38_20:22547671-22578642 |
Ensemble | ENSG00000259974 |
Refseq | NR_001558 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | qPCR |
Sample | non-small cell lung cancer tissues |
Expression Pattern | down-regulated |
Function Description | the LINC00261 expression level in NSCLC tissues was suppressed compared with that in adjacent normal lung tissues.Low expression of LINC00261 was found to significantly correlate with TNM stage, lymph node status, and distant metastasis.low LINC00261 expression level was associated with poorer overall survival.low expression of LINC00261 was an independent adverse prognostic factor of NSCLC. |
Pubmed ID | 29272004 |
Year | 2017 |
Title | Decreased expression of long non-coding RNA LINC00261 is a prognostic marker for patients with non-small cell lung cancer: a preliminary study. |
External Links
Links for LINC00261 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |