Basic Information
LncRNA/CircRNA Name | LINC00210 |
Synonyms | NA |
Region | GRCh38_1:217892900-217920804 |
Ensemble | ENSG00000231814 |
Refseq | NR_048550 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | Luciferase reporter assay etc |
Sample | NSCLC tissues, cell lines (SK-MES-1 and A549) |
Expression Pattern | up-regulated |
Function Description | The results demonstrated that LINC00210 was upregulated in NSCLC tissues and cell lines compared with that in normal tissues and 16-HBE cells, and that LINC00210 expression was associated with a poor prognosis in patients with NSCLC (P<0.05). Furthermore, A549 cell transfection with small interfering (si)LINC00210 and siLINC00210 induced a significant decrease in cell proliferation, and migratory and invasive abilities compared with that in the control groups (P<0.05). |
Pubmed ID | 32266029 |
Year | 2020 |
Title | LINC00210 plays oncogenic roles in non-small cell lung cancer by sponging microRNA-328-5p |
External Links
Links for LINC00210 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |