Basic Information
| LncRNA/CircRNA Name | LINC00173 |
| Synonyms | NA |
| Region | GRCh38_12:116533422-116536518 |
| Ensemble | ENSG00000196668 |
| Refseq | NR_027345 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | ESCC cell lines (ECA109 and KYSE410) |
| Expression Pattern | differential expression |
| Function Description | LINC00173 had negative coefficients suggested that higher levels of expression were related with longer survival. Colony formation assays showed that the knockdown of LINC00173 boosted the colony number. Cell cycle analysis demonstrated that LINC00173 knockdown led to a decreased G1/G0 population. |
| Pubmed ID | 29891973 |
| Year | 2018 |
| Title | A seven-lncRNA Signature Predicts Overall Survival in Esophageal Squamous Cell Carcinoma |
External Links
| Links for LINC00173 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |