Basic Information
| LncRNA/CircRNA Name | LINC00162 |
| Synonyms | PICSAR, C21orf113, LINC00162, NCRNA00162, NLC1-C, NLC1C, PRED74 |
| Region | GRCh38_21:44999208-45004727 |
| Ensemble | ENSG00000275874 |
| Refseq | NR_024089 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR |
| Sample | gastric cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | Here, we identified a long non-coding RNA, LINC00162, as highly and frequently expressed in gastric cancer cell lines sensitive to 5-aza-2??deoxycytidine (5-aza-dC). Knockdown of LINC00162 decreased the sensitivity while its overexpression increased the sensitivity. |
| Pubmed ID | 30914798 |
| Year | 2019 |
| Title | LINC00162 confers sensitivity to 5-Aza-2'-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1. |
External Links
| Links for LINC00162 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |