Basic Information
LncRNA/CircRNA Name | LINC00152 |
Synonyms | CYTOR, C2orf59, LINC00152, NCRNA00152 |
Region | GRCh38_2:87454781-87636740 |
Ensemble | ENSG00000222041 |
Refseq | NR_024204 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, RNAi, Western blot, Northern blot etc. |
Sample | gastric cancer tissues, cell lines (AGS, BGC-823, MGC-803, SGC-7901 etc.) |
Expression Pattern | up-regulated |
Function Description | The results showed that the expression level of LINC00152 in gastric carcinoma was significantly increased, compared with matched normal tissue and normal mucosa from health control, respectively. Levels of LINC00152 in gastric cancer cell lines, BGC-823, MGC-803, and SGC-7901, were significantly higher than those in human normal gastric epithelial cell line GES-1. In addition, high expression of LINC00152 was correlated with invasion. LINC00152 levels in gastric juice from patients with gastric cancer were further found significantly higher than those from normal controls. |
Pubmed ID | 24523021 |
Year | 2014 |
Title | Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance. |
External Links
Links for LINC00152 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |