Basic Information
| LncRNA/CircRNA Name | LEF1-AS1? |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qRT-PCR |
| Sample | ovarian cancer tissues,cell Lines |
| Expression Pattern | up-regulated |
| Function Description | LEF1-AS1 exerted its oncogenic functions through interacting with miR-1285-3p to inhibit miRNA activity. Rescue assay validated that miR-1285-3p inhibitors abrogated LEF1-AS1-silencer-caused suppression of ovarian cancer progression. |
| Pubmed ID | 32099465 |
| Year | 2020 |
| Title | LncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p |
External Links
| Links for LEF1-AS1? | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |