Basic Information
LncRNA/CircRNA Name | LCPAT1 |
Synonyms | NA |
Region | NA |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | lung cancer |
ICD-0-3 | C34 |
Methods | qPCR, Western blot, etc. |
Sample | cell lines (H1299, H520) |
Expression Pattern | up-regulated |
Function Description | Our results suggest that combined exposure to CSE and PM2.5 induces LCPAT1 expression, which up-regulates autophagy, and promotes lung cancer progression via RCC2. |
Pubmed ID | 29913439 |
Year | 2018 |
Title | LncRNA LCPAT1 Mediates Smoking/ Particulate Matter 2.5-Induced Cell Autophagy and Epithelial-Mesenchymal Transition in Lung Cancer Cells via RCC2. |
External Links
Links for LCPAT1 | GenBank HGNC NONCODE |
Links for lung cancer | OMIM COSMIC |